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Integrin beta 3 抗体

ITGB3 适用: 人, 灵长类 WB, FACS, IHC (fro) 宿主: 小鼠 Monoclonal VIPL2 unconjugated
产品编号 ABIN951364
发货至: 中国
  • 抗原 See all Integrin beta 3 (ITGB3) 抗体
    Integrin beta 3 (ITGB3)
    适用
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    人, 灵长类
    宿主
    • 115
    • 59
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    小鼠
    克隆类型
    • 111
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    单克隆
    标记
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    This Integrin beta 3 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody detects CD61, a 90-110 kDa transmembrane glycoprotein of integrin family, expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leucocytes and smooth muscle cells.
    交叉反应 (详细)
    Species reactivity (tested):Human, Non-Human Primates
    纯化方法
    Protein-A affinity chromatography
    纯度
    > 95 % pure by SDS-PAGE
    克隆位点
    VIPL2
    亚型
    IgG1
    Top Product
    Discover our top product ITGB3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Integrin beta 3 (ITGB3)
    别名
    CD61 / ITGB3 (ITGB3 产品)
    别名
    BDPLT16 antibody, BDPLT2 antibody, CD61 antibody, GP3A antibody, GPIIIa antibody, GT antibody, INGRB3 antibody, integrin antibody, INTB3 antibody, GPIIIA antibody, cd61 antibody, gp3a antibody, itgb3 antibody, itgb3.2 antibody, itgb3.1 antibody, integrin subunit beta 3 antibody, integrin beta 3 antibody, integrin subunit beta 3 L homeolog antibody, integrin beta 3a antibody, integrin beta 3b antibody, ITGB3 antibody, Itgb3 antibody, itgb3.L antibody, itgb3a antibody, itgb3b antibody
    背景
    CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 Molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa
    基因ID
    3690
    NCBI登录号
    NP_000203
    UniProt
    P05106
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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