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Integrin beta 3 抗体

ITGB3 适用: 人, 灵长类 WB, FACS, IHC (fro) 宿主: 小鼠 Monoclonal VIPL2 unconjugated
产品编号 ABIN951364
发货至: 中国
  • 抗原 See all Integrin beta 3 (ITGB3) 抗体
    Integrin beta 3 (ITGB3)
    适用
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    人, 灵长类
    宿主
    • 120
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    小鼠
    克隆类型
    • 115
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    单克隆
    标记
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    This Integrin beta 3 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))
    特异性
    This antibody detects CD61, a 90-110 kDa transmembrane glycoprotein of integrin family, expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leucocytes and smooth muscle cells.
    交叉反应 (详细)
    Species reactivity (tested):Human, Non-Human Primates
    纯化方法
    Protein-A affinity chromatography
    纯度
    > 95 % pure by SDS-PAGE
    克隆位点
    VIPL2
    亚型
    IgG1
    Top Product
    Discover our top product ITGB3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Integrin beta 3 (ITGB3)
    别名
    CD61 / ITGB3 (ITGB3 产品)
    背景
    CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 Molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa
    基因ID
    3690
    NCBI登录号
    NP_000203
    UniProt
    P05106
    途径
    Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
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