Integrin beta 3 抗体
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北京 101111
Quick Overview for Integrin beta 3 抗体 (ABIN951364)
抗原
See all Integrin beta 3 (ITGB3) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody detects CD61, a 90-110 kDa transmembrane glycoprotein of integrin family, expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leucocytes and smooth muscle cells.
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交叉反应 （详细）
- Species reactivity (tested):Human, Non-Human Primates
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纯化方法
- Protein-A affinity chromatography
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纯度
- > 95 % pure by SDS-PAGE
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亚型
- IgG1
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anti-Integrin beta 3 (ITGB3) (AA 27-120) antibody
ITGB3 适用: 人, 小鼠 WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) (AA 134-376) antibodyITGB3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) antibodyITGB3 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Integrin beta 3 (ITGB3) (AA 27-179) antibodyITGB3 适用: 人 IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 3E8A6 unconjugated
anti-Integrin beta 3 (ITGB3) (AA 610-718) antibodyITGB3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) (AA 385-490) antibodyITGB3 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ITGB3-2145 unconjugated
anti-Integrin beta 3 (ITGB3) antibody (FITC)ITGB3 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal VIPL2 FITC
anti-Integrin beta 3 (ITGB3) antibody (PerCP)ITGB3 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal VIPL2 PerCP
anti-Integrin beta 3 (ITGB3) (AA 734-760) antibodyITGB3 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Integrin beta 3 (ITGB3) (AA 135-377) antibodyITGB3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- Integrin beta 3 (ITGB3)
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别名
- CD61 / ITGB3
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背景
- CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 Molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells.Synonyms: GP3A, GPIIIa, Integrin beta-3, Platelet membrane glycoprotein IIIa
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基因ID
- 3690
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NCBI登录号
- NP_000203
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UniProt
- P05106
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex
抗原
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