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CD27 抗体

This anti-CD27 antibody is a 仓鼠 单克隆 antibody detecting CD27 in FACS, IHC (p), IHC (fro) 和 Func. Suitable for 小鼠.
产品编号 ABIN951256
发货至: 中国

Quick Overview for CD27 抗体 (ABIN951256)

抗原

See all CD27 抗体
CD27 (CD27 Molecule (CD27))

适用

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小鼠

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仓鼠

克隆类型

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单克隆

标记

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This CD27 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

克隆位点

LG-3A10
  • 特异性

    Recognizes Mouse CD27 receptor.

    交叉反应 (详细)

    Species reactivity (tested):Mouse.

    纯化方法

    Protein G Chromatography.

    免疫原

    MCD27 tag expressing clones AR0524 and AR0530 from Armenian Hamster spleen.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CD27 (CD27 Molecule (CD27))

    别名

    CD27

    背景

    CD27 is part of the Tumor Necrosis Factor (TNF) family of receptors and is lymphocyte specific. Murine CD27 is expressed on the great majority of both and T lymphocytes, on a small population of peripheral B cells and on a very small subset of B220+ cells in the bone marrow. Murine CD27 is found on all thymocytes except a subset of CD4-CD8- precursors. There are two known basic functions of CD27 signaling. First, the binding of CD27 to CD70, a protein which is also expressed in T and B cells, provides costimulatory signals in lymphocyte proliferation and immunoglobulin production. Second, the association of CD27 with intracellular Siva, a proapoptotic protein, results in the induction of apoptotic events.Synonyms: CD27L receptor, T-cell activation antigen CD27, T14, TNFRSF7, Tumor necrosis factor receptor superfamily member 7

    基因ID

    21940

    NCBI登录号

    NP_001028298

    UniProt

    P41272

    途径

    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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