CD27 抗体 (Biotin)
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北京 101111
Quick Overview for CD27 抗体 (Biotin) (ABIN951254)
抗原
See all CD27 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This Monoclonal Antibody is specific for the Mouse CD27 receptor.
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免疫原
- MCD27 tag expressing clones AR0524 and AR0530 Donor: Armenian hamster spleen Fusion Partner: SP2/0 Murine Myeloma Partner
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0,1 mg/mL
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缓冲液
- PBS, 0.02 % Sodium Azide, EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CD27 (CD27 Molecule (CD27))
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别名
- CD27
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背景
- CD27 is part of the Tumor Necrosis Factor (TNF) family of receptors and is lymphocyte specific. Murine CD27 is expressed on the great majority of both αβ and γδ T lymphocytes, on a small population of peripheral B cells and on a very small subset of B220+ cells in the bone marrow. Murine CD27 is found on all thymocytes except a subset of CD4-CD8-precursors. There are two known basic functions of CD27 signaling. First, the binding of CD27 to CD70, a protein which is also expressed in T and B cells, provides costimulatory signals in lymphocyte proliferation and immunoglobulin production. Second, the association of CD27 with intracellular Siva, a proapoptotic protein, results in the induction of apoptotic events.Synonyms: CD27L receptor, T-cell activation antigen CD27, T14, TNFRSF7, Tumor necrosis factor receptor superfamily member 7
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基因ID
- 21940
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NCBI登录号
- NP_001028298
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UniProt
- P41272
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途径
- Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
抗原
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