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MUC1 抗体 (AA 1209-1239)

MUC1 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN951233
发货至: 中国
  • 抗原 See all MUC1 抗体
    MUC1 (Mucin 1 (MUC1))
    抗原表位
    • 26
    • 19
    • 16
    • 16
    • 12
    • 8
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1209-1239
    适用
    • 270
    • 58
    • 30
    • 12
    • 6
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 196
    • 87
    • 2
    • 1
    克隆类型
    • 174
    • 107
    • 5
    多克隆
    标记
    • 145
    • 26
    • 16
    • 11
    • 11
    • 10
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This MUC1 antibody is un-conjugated
    应用范围
    • 140
    • 136
    • 102
    • 84
    • 75
    • 48
    • 26
    • 24
    • 24
    • 20
    • 19
    • 14
    • 13
    • 13
    • 6
    • 6
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes human CD227 / Mucin-1 / MUC1.
    纯化方法
    Purified through a Protein A column followed by peptide affinity purification
    免疫原
    Synthetic peptide - KLH conjugated - corresponding to human CD227 / Mucin-1 / MUC1 (between 1209-1239aa)
    亚型
    Ig Fraction
    Top Product
    Discover our top product MUC1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) Sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    MUC1 (Mucin 1 (MUC1))
    别名
    CD227 / Mucin-1 / MUC1 (MUC1 产品)
    别名
    CA 15-3 antibody, CD227 antibody, EMA antibody, H23AG antibody, KL-6 antibody, MAM6 antibody, MCKD1 antibody, MUC-1 antibody, MUC-1/SEC antibody, MUC-1/X antibody, MUC1/ZD antibody, PEM antibody, PEMT antibody, PUM antibody, Muc-1 antibody, mucin 1, cell surface associated antibody, mucin 1, transmembrane antibody, MUC1 antibody, Muc1 antibody
    背景
    The MUC1 gene is a member of the mucin family and encodes a membrane bound, glyco- sylated phosphoprotein anchored to the apical surface of many epithelia by a transmem- brane domain, with the degree of glycosylation varying with cell type. It includes a 20aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Its overexpression, aberrant intracellular localization and changes in glycosylation have been associated with carcino- mas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined.Synonyms: Breast carcinoma-associated antigen DF3, CA 15-3, Carcinoma-associated mucin, DF3, EMA, Episialin, H23AG, MUC-1, PEMT, PUM, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin
    分子量
    122102 Da
    基因ID
    4582
    NCBI登录号
    NP_001018016
    途径
    Negative Regulation of intrinsic apoptotic Signaling
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