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MUC1 抗体 (AA 1209-1239)

This anti-MUC1 antibody is a 兔 多克隆 antibody detecting MUC1 in WB 和 EIA. Suitable for 人.
产品编号 ABIN951233
发货至: 中国

Quick Overview for MUC1 抗体 (AA 1209-1239) (ABIN951233)

抗原

See all MUC1 抗体
MUC1 (Mucin 1 (MUC1))

适用

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克隆类型

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多克隆

标记

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This MUC1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 1209-1239

    特异性

    This antibody recognizes human CD227 / Mucin-1 / MUC1.

    纯化方法

    Purified through a Protein A column followed by peptide affinity purification

    免疫原

    Synthetic peptide - KLH conjugated - corresponding to human CD227 / Mucin-1 / MUC1 (between 1209-1239aa)

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) Sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    MUC1 (Mucin 1 (MUC1))

    别名

    CD227 / Mucin-1 / MUC1

    背景

    The MUC1 gene is a member of the mucin family and encodes a membrane bound, glyco- sylated phosphoprotein anchored to the apical surface of many epithelia by a transmem- brane domain, with the degree of glycosylation varying with cell type. It includes a 20aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Its overexpression, aberrant intracellular localization and changes in glycosylation have been associated with carcino- mas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined.Synonyms: Breast carcinoma-associated antigen DF3, CA 15-3, Carcinoma-associated mucin, DF3, EMA, Episialin, H23AG, MUC-1, PEMT, PUM, Peanut-reactive urinary mucin, Polymorphic epithelial mucin, Tumor-associated epithelial membrane antigen, Tumor-associated mucin

    分子量

    122102 Da

    基因ID

    4582

    NCBI登录号

    NP_001018016

    途径

    Negative Regulation of intrinsic apoptotic Signaling
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