SLAMF1 抗体
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Quick Overview for SLAMF1 抗体 (ABIN951192)
抗原
See all SLAMF1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This Monoclonal SLAM.4 antibody recognizes CD150, a cell surface molecule expressed on lymphocytes and involved in their activation.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Protein A-affinity chromatography
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免疫原
- Human CD150-transfected 300.19 cells
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL (> 95% pure by SDS-PAGE)
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缓冲液
- Azide free phosphate buffered saline (PBS), pH ~7.4, 0.2 μm filter sterilized
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储存液
- Azide free
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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- SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
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别名
- CD150 / SLAMF1
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背景
- CD150, also known as SLAM (signaling lymphocyte activation molecule) is a 70-95 kDa single chain transmembrane phosphoglycoprotein of the CD2 family. Its extracellular part contains eight potential N-glycosylation sites, and the intracellular tail contains three unique tyrosine-based motifs. These binding sites can be recognized by SH2-binding phosphatases and the adaptor proteins, such as SAP/SH2D1A or EAT-2. The SLAM family receptors are involved in leucocyte activation and contribute to the effective germinal center formation, generation of high-affinity antibody-secreting plasma cells, and memory T and B cells, thereby facilitating long-term immune response. CD150 expression is upregulated after cell activation.Synonyms: CDw150, Ipo-3, Signaling lymphocytic activation molecule, Slam
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基因ID
- 6504
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NCBI登录号
- NP_003028
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UniProt
- Q13291
抗原
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