(2 references)-
- 抗原 See all SLAMF1 抗体
- SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SLAMF1 antibody is conjugated to PE
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应用范围
- Flow Cytometry (FACS)
- 特异性
- The mouse monoclonal antibody SLAM.4 recognizes an extracellular epitope of CD150, a cell surface molecule expressed on lymphocytes and involved in their activation.
- 交叉反应 （详细）
- Human
- 纯化方法
- Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
- 免疫原
- Human CD150-transfected 300.19 cells
- 克隆位点
- SLAM-4
- 亚型
- IgG1
- Top Product
- Discover our top product SLAMF1 Primary Antibody
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anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (AA 19-236) antibody
SLAMF1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (Tyr1096) antibodySLAMF1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (AA 231-335) antibodySLAMF1 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (AA 69-204) antibodySLAMF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) antibodySLAMF1 适用: 人 FACS, IP, ICC 宿主: 小鼠 Monoclonal SLAM-4 unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) antibody (FITC)SLAMF1 适用: 人 FACS 宿主: 小鼠 Monoclonal SLAM-4 FITC
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (pTyr281) antibodySLAMF1 适用: 人 ELISA, DB 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (C-Term) antibodySLAMF1 适用: 人, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) antibody (APC)SLAMF1 适用: 人 FACS 宿主: 小鼠 Monoclonal SLAM-4 APC
anti-Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1) (AA 21-237) antibodySLAMF1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 10 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (1 ml) is sufficient for 100 tests.
- 说明
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The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. No reconstitution is necessary.
- 限制
- 仅限研究用
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- 缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).
: "Differential expression of SAP and EAT-2-binding leukocyte cell-surface molecules CD84, CD150 (SLAM), CD229 (Ly9) and CD244 (2B4)." in: Tissue antigens, Vol. 64, Issue 2, pp. 132-44, (2004) (PubMed).
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: "CD229 (Ly9) lymphocyte cell surface receptor interacts homophilically through its N-terminal domain and relocalizes to the immunological synapse." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 11, pp. 7033-42, (2005) (PubMed).
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- 抗原
- SLAMF1 (Signaling Lymphocytic Activation Molecule Family Member 1 (SLAMF1))
- 别名
- CD150 (SLAMF1 产品)
- 别名
- CD150 antibody, SLAM antibody, SLAMF1 antibody, 4933415F16 antibody, AA177906 antibody, CDw150 antibody, ESTM51 antibody, IPO-3 antibody, Slam antibody, RGD1560634 antibody, signaling lymphocytic activation molecule family member 1 antibody, SLAMF1 antibody, Slamf1 antibody
- 背景
- Signaling lymphocytic activation molecule family m,CD150, also known as SLAM (signaling lymphocyte activation molecule) is a 70-95 kDa single chain transmembrane phosphoglycoprotein of the CD2 family. Its extracellular part contains eight potential N-glycosylation sites, and the intracellular tail contains three unique tyrosine-based motifs. These binding sites can be recognized by SH2-binding phosphatases and the adaptor proteins, such as SAP/SH2D1A or EAT-2. The SLAM family receptors are involved in leucocyte activation and contribute to the effective germinal center formation, generation of high-affinity antibody-secreting plasma cells, and memory T and B cells, thereby facilitating long-term immune response. CD150 expression is upregulated after cell activation.,SLAM, SLAMF1
- 基因ID
- 6504
- UniProt
- Q13291
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