BCL3 抗体
Quick Overview for BCL3 抗体 (ABIN950631)
抗原
See all BCL3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- Recognizes B-cell Leukemia/lymphoma 3
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交叉反应 （详细）
- Species reactivity (tested):Human and Mouse.
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纯化方法
- Protein G Affinity Chromatography.
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免疫原
- Recombinant Bcl-3-6-histidine tag from Armenian Hamster. Fusion Partner: SP2/0 myeloma
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亚型
- IgG1
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anti-B-Cell CLL/lymphoma 3 (BCL3) (AA 300-400) antibody
BCL3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 3 (BCL3) (AA 362-454) antibodyBCL3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 3 (BCL3) (C-Term) antibodyBCL3 适用: 人 WB, ELISA, IHC, IP, IF, FACS, FM 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 3 (BCL3) (AA 248-277), (Middle Region) antibodyBCL3 适用: 人, 小鼠 WB, IF, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 3 (BCL3) (C-Term) antibodyBCL3 适用: 人 WB, ELISA, IHC, IP, IF, FACS, FM 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 3 (BCL3) (AA 82-341) antibodyBCL3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 3 (BCL3) (AA 1-446) antibodyBCL3 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 3 (BCL3) (AA 1-446) antibodyBCL3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 3 (BCL3) antibodyBCL3 适用: 人 WB, ICC, DB 宿主: 小鼠 Monoclonal 2069E2a unconjugated
anti-B-Cell CLL/lymphoma 3 (BCL3) (AA 127-376) antibodyBCL3 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
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别名
- Bcl-3
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背景
- B cell Lymphoma 3 is a member of the IkB subfamily of inhibitors. This subfamily is part of the NF-kB transcription factor protein family and it is suggested that a balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells. Bcl-3 has been shown to have versatile functions such as cytoplasmic activation of p50 homodimers, translocation to the nucleus, and modulation of the transcriptional machinery in the nucleus. Bcl-3 activity often relies on several nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin. The Mouse Bcl-3 coding region exhibits 80 % homology with Human Bcl-3 which is associated with human B-cell chronic lymphocytic leukemias (CLLs). Bcl-3 is detected in various tissues such as spleen and other lymphoid organs.Synonyms: B-cell lymphoma 3-encoded protein, BCL3, BCL4, D19S37
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基因ID
- 602
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NCBI登录号
- NP_005169
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UniProt
- P20749
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途径
- NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus
抗原
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