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BCL3 抗体 (C-Term)

BCL3 适用: 人 WB, ELISA, IHC, IP, FACS, FM 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6655290
发货至: 中国
  • 抗原 See all BCL3 抗体
    BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
    抗原表位
    • 15
    • 7
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    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    C-Term
    适用
    • 42
    • 41
    • 3
    • 1
    宿主
    • 49
    • 12
    • 5
    克隆类型
    • 51
    • 15
    多克隆
    标记
    • 28
    • 7
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This BCL3 antibody is un-conjugated
    应用范围
    • 43
    • 15
    • 13
    • 13
    • 9
    • 7
    • 7
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    • 4
    • 3
    • 3
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP), Flow Cytometry (FACS), Fluorescence Microscopy (FM)
    纯化方法
    This affinity purified antibody is directed against human BCL3. This product was affinity purified from monospecific antiserum by immunoaffinity purification. Blast analysis of the sequence of the immunogen shows 100% identity with human.
    免疫原

    Immunogen: Anti-BCL3 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to a C-Term portion of human BCL3 conjugated to Keyhole Limpet Hemocyanin (KLH).

    Immunogen Type: Peptide

    亚型
    IgG
    Top Product
    Discover our top product BCL3 Primary Antibody
  • 应用备注

    Immunohistochemistry Dilution: 1:200

    Application Note: Anti-BCL-3 Antibody has been tested in Western Blot, ELISA, and Immunofluorescence. Expect a band at 47.5 kDa in western blot using appropriate lysates. Positive control used recombinant BCL3 protein, HEK293T overexpressing BCL3 or U87 whole cell lysates at 1 μg/mL in WB, and U87MG with PFA at 10 μg/mL in IF. Although not tested, this antibody is likely functional in immunohistochemistry, flow cytometry, and immunoprecipitation.

    Immunoprecipitation Dilution: User Optimized

    ELISA Dilution: 5.0 μg/mL

    Flow Cytometry Dilution: User Optimized

    Western Blot Dilution: 1:1000

    IF Microscopy Dilution: 10 μg/mL

    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液

    Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2

    0.01 % (w/v) Sodium Azide

    Stabilizer: None

    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    RT,4 °C,-20 °C
    储存方法
    Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
  • 抗原
    BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
    别名
    BCL3 (BCL3 产品)
    别名
    BCL3 antibody, AI528691 antibody, Bcl-3 antibody, BCL4 antibody, D19S37 antibody, B-cell CLL/lymphoma 3 antibody, B cell leukemia/lymphoma 3 antibody, BCL3 antibody, Bcl3 antibody
    背景

    Synonyms: rabbit anti-BCL3 antibody, rabbit anti-BCL-3 Antibody, BCL 3, B-cell lymphoma 3 protein, B-cell lymphoma 3 protein Antibody

    Background: BCL3 belongs to the ANKRD family. The protein contains seven ankyrin repeats, which are closely related to those found in I kappa B proteins. BCL3 functions as a transcriptional co-activator, regulator of transcriptional activation, promotor of transcription, and inhibitor of nuclear translocation of NF-kappa B. It is a proto-oncogene identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. BCL3 contributes to the regulation of cell proliferation. Therefore, BCL3 may be associated with B-cell chronic lymphocytic leukemia, lymphoma, or other hematologic diseases. Anti-BCL3 Antibody is useful for researchers interested in Cancer Research, NF-Kappa B Pathway, and TNF Signaling Pathway.

    Gene Name: BCL3

    基因ID
    602
    NCBI登录号
    NP_005169
    UniProt
    P20749
    途径
    NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus
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