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BCL3 抗体 (FITC)

BCL3 适用: 人, 小鼠 FACS 宿主: 仓鼠 Monoclonal Ham150-3-5 FITC
产品编号 ABIN950630
发货至: 中国
  • 抗原 See all BCL3 抗体
    BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
    适用
    • 42
    • 40
    • 3
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    人, 小鼠
    宿主
    • 50
    • 11
    • 5
    仓鼠
    克隆类型
    • 52
    • 14
    单克隆
    标记
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    This BCL3 antibody is conjugated to FITC
    应用范围
    • 44
    • 16
    • 13
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    • 9
    • 7
    • 7
    • 7
    • 4
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    Flow Cytometry (FACS)
    特异性
    Recognizes B-cell Leukemia/lymphoma 3
    交叉反应 (详细)
    Species reactivity (tested):Human and Mouse.
    纯化方法
    Protein G Affinity Chromatography.
    免疫原
    Recombinant Bcl-3-6-histidine tag from Armenian Hamster. Fusion Partner: SP2/0 myeloma.
    克隆位点
    Ham150-3-5
    亚型
    IgG1
    Top Product
    Discover our top product BCL3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    BCL3 (B-Cell CLL/lymphoma 3 (BCL3))
    别名
    Bcl-3 (BCL3 产品)
    别名
    BCL3 antibody, AI528691 antibody, Bcl-3 antibody, BCL4 antibody, D19S37 antibody, B-cell CLL/lymphoma 3 antibody, B cell leukemia/lymphoma 3 antibody, BCL3 antibody, Bcl3 antibody
    背景
    B cell Lymphoma 3 is a member of the IkB subfamily of inhibitors. This subfamily is part of the NF-kB transcription factor protein family and it is suggested that a balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells. Bcl-3 has been shown to have versatile functions such as cytoplasmic activation of p50 homodimers, translocation to the nucleus, and modulation of the transcriptional machinery in the nucleus. Bcl-3 activity often relies on several nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin. The Mouse Bcl-3 coding region exhibits 80 % homology with Human Bcl-3 which is associated with human B-cell chronic lymphocytic leukemias (CLLs). Bcl-3 is detected in various tissues such as spleen and other lymphoid organs.Synonyms: B-cell lymphoma 3-encoded protein, BCL3, BCL4, D19S37
    基因ID
    602
    NCBI登录号
    NP_005169
    UniProt
    P20749
    途径
    NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus
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