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BCL3 抗体 (FITC)

This anti-BCL3 antibody is a 仓鼠 单克隆 antibody detecting BCL3 in FACS. Suitable for 人 和 小鼠.
产品编号 ABIN950630
发货至: 中国

Quick Overview for BCL3 抗体 (FITC) (ABIN950630)

抗原

See all BCL3 抗体
BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

适用

  • 37
  • 36
  • 6
人, 小鼠

宿主

  • 47
  • 7
  • 5
仓鼠

克隆类型

  • 49
  • 10
单克隆

标记

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  • 1
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  • 1
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  • 1
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  • 1
  • 1
  • 1
  • 1
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This BCL3 antibody is conjugated to FITC

应用范围

  • 46
  • 19
  • 13
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  • 3
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Flow Cytometry (FACS)

克隆位点

Ham150-3-5
  • 特异性

    Recognizes B-cell Leukemia/lymphoma 3

    交叉反应 (详细)

    Species reactivity (tested):Human and Mouse.

    纯化方法

    Protein G Affinity Chromatography.

    免疫原

    Recombinant Bcl-3-6-histidine tag from Armenian Hamster. Fusion Partner: SP2/0 myeloma.

    亚型

    IgG1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

    别名

    Bcl-3

    背景

    B cell Lymphoma 3 is a member of the IkB subfamily of inhibitors. This subfamily is part of the NF-kB transcription factor protein family and it is suggested that a balance in the concentration of various NF-kB family members regulates apoptosis and survival of activated T cells. Bcl-3 has been shown to have versatile functions such as cytoplasmic activation of p50 homodimers, translocation to the nucleus, and modulation of the transcriptional machinery in the nucleus. Bcl-3 activity often relies on several nuclear interacting proteins such as Tip60, Jab1, Bard1, and Pirin. The Mouse Bcl-3 coding region exhibits 80 % homology with Human Bcl-3 which is associated with human B-cell chronic lymphocytic leukemias (CLLs). Bcl-3 is detected in various tissues such as spleen and other lymphoid organs.Synonyms: B-cell lymphoma 3-encoded protein, BCL3, BCL4, D19S37

    基因ID

    602

    NCBI登录号

    NP_005169

    UniProt

    P20749

    途径

    NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus
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