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Axin 抗体 (C-Term)

This anti-Axin antibody is a 兔 多克隆 antibody detecting Axin in WB 和 EIA. Suitable for 人.
产品编号 ABIN950582
发货至: 中国

Quick Overview for Axin 抗体 (C-Term) (ABIN950582)

抗原

See all Axin (AXIN1) 抗体
Axin (AXIN1) (Axin 1 (AXIN1))

适用

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宿主

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克隆类型

  • 94
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多克隆

标记

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This Axin antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 717-746, C-Term

    特异性

    This antibody reacts to Axin-1.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 717-746 amino acids from the C-terminal region of human AXIN1

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) sodium azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    Axin (AXIN1) (Axin 1 (AXIN1))

    别名

    Axin-1

    背景

    This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene.Synonyms: AXIN, AXIN1, Axis inhibition protein 1

    基因ID

    8312

    NCBI登录号

    NP_003493

    途径

    WNT signaling, Sensory Perception of Sound, Regulation of G-Protein Coupled Receptor Protein Signaling
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