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beta Arrestin 1 抗体 (C-Term)

This anti-beta Arrestin 1 antibody is a 兔 多克隆 antibody detecting beta Arrestin 1 in WB, IF, IHC (p), FACS 和 EIA. Suitable for 人.
产品编号 ABIN950521
发货至: 中国
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Quick Overview for beta Arrestin 1 抗体 (C-Term) (ABIN950521)

抗原

See all beta Arrestin 1 (ARRB1) 抗体
beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))

适用

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宿主

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克隆类型

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多克隆

标记

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This beta Arrestin 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
  • 抗原表位

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    AA 343-371, C-Term

    特异性

    This antibody reacts to Arrestin beta-1.

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Affinity chromatography on Protein A

    免疫原

    KLH conjugated synthetic peptide between 343-371 amino acids from the C-terminal region of human ARRB1

    亚型

    Ig Fraction
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.25 mg/mL

    缓冲液

    PBS containing 0.09 % (W/V) sodium azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))

    别名

    Arrestin beta-1 / ARRB1

    背景

    Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known.Synonyms: ARR1, Beta-arrestin-1

    基因ID

    408

    NCBI登录号

    NP_004032

    途径

    Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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