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L-Selectin 抗体

This anti-L-Selectin antibody is a 小鼠 单克隆 antibody detecting L-Selectin in FACS, IP 和 ICC. Suitable for 人 和 Cow. This Primary Antibody has been cited in 3+ publications.
产品编号 ABIN94209
发货至: 中国

Quick Overview for L-Selectin 抗体 (ABIN94209)

抗原

See all L-Selectin (SELL) 抗体
L-Selectin (SELL) (Selectin L (SELL))

适用

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人, Cow

宿主

  • 93
  • 55
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  • 3
  • 1
小鼠

克隆类型

  • 150
  • 51
  • 4
单克隆

标记

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  • 1
  • 1
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This L-Selectin antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Immunoprecipitation (IP), Immunocytochemistry (ICC)

克隆位点

IVA94
  • 原理

    Anti-Bov CD62L Purified

    特异性

    The antibody IVA94 reacts with an extracellular epitope of CD62L antigen (bovine). CD62L (L-selectin) is a 74-95 kDa single chain type I glycoprotein expressed on most peripheral blood B lymphocytes, T lymphocytes, monocytes and granulocytes, it is also present on a subset of NK cells and certain hematopoietic malignant cells.

    交叉反应 (详细)

    Bovine

    纯化方法

    Purified by protein-A affinity chromatography.

    纯度

    > 95 % (by SDS-PAGE)

    免疫原

    Bovine leukocytes.

    亚型

    IgG1
  • 应用备注

    Flow cytometry: Recommended dilution: 1-4 μg/mL.

    限制

    仅限研究用
  • 浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Do not freeze.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Do not freeze.
  • Howard: "Ruminant cluster CD62L." in: Veterinary immunology and immunopathology, Vol. 52, Issue 4, pp. 255-6, (1997) (PubMed).

    Naessens, Nthale, Muiya: "Biochemical analysis of preliminary clusters in the non-lineage panel." in: Veterinary immunology and immunopathology, Vol. 52, Issue 4, pp. 347-56, (1997) (PubMed).

    Naessens, Howard, Hopkins: "Nomenclature and characterization of leukocyte differentiation antigens in ruminants." in: Immunology today, Vol. 18, Issue 8, pp. 365-8, (1997) (PubMed).

  • 抗原

    L-Selectin (SELL) (Selectin L (SELL))

    别名

    CD62L

    背景

    Selectin L,CD62L (L-selectin) is an adhesion glycoprotein that is constitutively expressed on the cell surface of leukocytes and mediates their homing to inflammatory sites and peripheral lymph nodes by enabling rolling along the venular wall. CD62L is also involved in activation-induced neutrophil aggregation. Activation-dependent CD62L shedding, however, counteracts neutrophil rolling. CD62L has also signaling roles including enhance of chemokine receptor expression. Similarly to CD62P, the major ligand of CD62L is PSGL-1 (P-selectin glycoprotein ligand-1).,L-selectin, LSEL, SELL, LAM1, LECAM1, LEU8, LNHR, LYAM1, PLNHR

    基因ID

    281485

    UniProt

    P98131
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