CD44 抗体 (FITC)
(3 references)Quick Overview for CD44 抗体 (FITC) (ABIN94125)
抗原
See all CD44 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Hu CD44 FITC
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特异性
- The antibody MEM-85 reacts with an extracellular antigen of both cell surface-expressed and soluble form of CD44 antigen (Phagocyte glycoprotein 1), a 80-95 kDa transmembrane glycoprotein (hyaladherin family) present on the most of cells and tissues (leukocytes, endothelial cells, mesenchymal cells, etc.), it is negative on platelets and hepatocytes.
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交叉反应 （详细）
- Human
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纯化方法
- Purified antibody is conjugated with fluorescein isothiocyanate (FITC) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.
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免疫原
- Leukocytes of a patient suffering from LGL Type Leukaemia.
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亚型
- IgG2b
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anti-CD44 (CD44) antibody
CD44 适用: 人, 小鼠 FACS, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 8E2F3 unconjugated
anti-CD44 (CD44) antibodyKO Validated CD44 适用: 人 WB, IF, IHC (p), IP, IHC (fro), ICC, LCI 宿主: 兔 Polyclonal unconjugated
anti-CD44 (CD44) (AA 21-220) antibodyCD44 适用: 人 FACS, WB, IHC, ELISA, IF 宿主: 小鼠 Monoclonal 6G2D2 unconjugated
anti-CD44 (CD44) antibodyCD44 适用: 人 FACS, WB, IHC, ELISA, IHC (p), IP, Inhibition 宿主: 小鼠 Monoclonal MEM-85 unconjugated
anti-CD44 (CD44) antibodyCD44 适用: 人, 犬, Pig FACS, WB, IHC (p), IP 宿主: 小鼠 Monoclonal MEM-263 unconjugated
anti-CD44 (CD44) (AA 148-247) antibodyCD44 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-CD44 (CD44) (AA 36-194) antibodyCD44 适用: 人 FACS, WB, IHC, ELISA 宿主: 小鼠 Monoclonal 7F4F1 unconjugated
anti-CD44 (CD44) (AA 21-259) antibodyCD44 适用: 人, 小鼠, 大鼠 FACS, WB, IHC, ELISA, IF, IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-CD44 (CD44) (AA 1-361) antibodyCD44 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-CD44 (CD44) antibodyCD44 适用: 人, Baboon, Green Monkey FACS, WB, IHC, IF, Func, StM 宿主: 小鼠 Monoclonal 156-3C11 unconjugated
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应用备注
- Flow cytometry: The reagent is designed for analysis of human blood cells using 20 μL reagent / 100 μL of whole blood or 106 cells in a suspension. The content of a vial (2 ml) is sufficient for 100 tests.
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限制
- 仅限研究用
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溶解方式
- No reconstitution is necessary.
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缓冲液
- Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
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Do not freeze.
Avoid prolonged exposure to light. -
储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
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: "A novel human B cell subpopulation representing the initial germinal center population to express AID." in: Blood, Vol. 109, Issue 6, pp. 2545-52, (2007) (PubMed).
: "Metalloprotease and serine protease are involved in cleavage of CD43, CD44, and CD16 from stimulated human granulocytes. Induction of cleavage of L-selectin via CD16." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 152, Issue 3, pp. 1314-22, (1994) (PubMed).
: "Human leucocyte surface glycoprotein CDw44 and lymphocyte homing receptor are identical molecules." in: Immunogenetics, Vol. 29, Issue 6, pp. 402-4, (1989) (PubMed).
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: "A novel human B cell subpopulation representing the initial germinal center population to express AID." in: Blood, Vol. 109, Issue 6, pp. 2545-52, (2007) (PubMed).
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- CD44
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别名
- CD44
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背景
- CD44 Molecule,CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumour growth and metastasis, antiapoptosis and directional motility of cancer cells.,PGP-I, HUTCH-I, ECMR-III, Hermes antigen, Hyaluronate receptor, Heparan sulfate proteoglycan, Epican, MC56, MIC4, INLU, LHR
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基因ID
- 960
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UniProt
- P16070
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途径
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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