PAPPA 抗体
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北京 101111
Quick Overview for PAPPA 抗体 (ABIN934003)
抗原
See all PAPPA 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Protein A affinity chromatography
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免疫原
- PAPPA antibody was raised in mouse using purified human PAPP-A/proMBP complex or purified human atherosclerotic tissue form of PAPP-A as the immunogen.
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亚型
- IgG2b
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应用备注
- Optimal conditions should be determined byt he investigator.
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限制
- 仅限研究用
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浓度
- Lot specific
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缓冲液
- PBS, pH 7.4, 0.1 % NaN3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C
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- PAPPA (Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))
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别名
- PAPPA
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背景
- Pregnancy-associated plasma protein A, pappalysin 1, also known as PAPPA, is a protein used in screening tests for Down syndrome. PAPPA is a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses. Synonyms: Monoclonal PAPPA antibody, Anti-PAPPA antibody, PAPP-A antibody, PAPP A antibody, Pregnancy Associated Plasma Protein A antibody.
抗原
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