PAPPA antibody was raised in mouse using purified human PAPP-A/proMBP complex or purified human atherosclerotic tissue form of PAPP-A as the immunogen.
Optimal conditions should be determined byt he investigator.
限制
仅限研究用
浓度
Lot specific
缓冲液
PBS, pH 7.4, 0.1 % NaN3.
储存液
Sodium azide
注意事项
This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
储存条件
4 °C
抗原
PAPPA
(Pregnancy-Associated Plasma Protein A, Pappalysin 1 (PAPPA))
别名
PAPPA
背景
Pregnancy-associated plasma protein A, pappalysin 1, also known as PAPPA, is a protein used in screening tests for Down syndrome. PAPPA is a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses. Synonyms: Monoclonal PAPPA antibody, Anti-PAPPA antibody, PAPP-A antibody, PAPP A antibody, Pregnancy Associated Plasma Protein A antibody.