TGFB1 抗体
Our Local Distributor
北京 101111
Quick Overview for TGFB1 抗体 (ABIN932231)
抗原
See all TGFB1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
免疫原
- TGF beta 1 antibody was raised in Mouse using a purified recombinant fragment of TGFbeta1 expressed in E. coli as the immunogen.
-
亚型
- IgG2a
-
-
-
-
应用备注
-
ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
注意事项
-
Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 4 °C for short term storage. Store at -20 °C for long term storage.
-
-
- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
-
别名
- TGF beta 1
-
背景
- TGF beta is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. In mammals, three isoforms of TGFbeta, that is, beta1, beta2,and beta3 are known. TGF beta is one of numerous inhibitory factors produced by cancer cells that regulate antitumor immunity. TGF beta1 takes part in the local response in the course of primary lung cancer and TGFbeta1 is thought to be implicated in breast cancer progression. TGFbeta1 also plays a critical role in the downregulation of microglial responses minimizing brain inflammation and thus avoiding exacerbation of brain damage. Synonyms: Monoclonal TGF beta 1 antibody, Anti-TGF beta 1 antibody, Transforming growth factor beta antibody.
-
途径
- EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints
抗原
-