ERBB3 抗体 (AA 1175-1275)
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北京 101111
Quick Overview for ERBB3 抗体 (AA 1175-1275) (ABIN931388)
抗原
See all ERBB3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1175-1275
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免疫原
- ERBB3 antibody was raised in Mouse using a purified recombinant fragment of ERBB3(aa1175-1275) expressed in E. coli as the immunogen.
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亚型
- IgG1
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应用备注
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ELISA: 1:10,000, WB: 1:500-1:2000
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
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Avoid repeated freeze/thaw cycles.
Dilute only prior to immediate use. -
储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C for short term storage. Store at -20 °C for long term storage.
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- ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
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别名
- ERBB3
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背景
- ERBB3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Synonyms: Monoclonal ERBB3 antibody, Anti-ERBB3 antibody, V-erb-b2 antibody, Erythroblastic leukemia viral oncogene homolog 3 antibody.
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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