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ERBB3 抗体 (AA 1175-1275)

ERBB3 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 3F10F6 unconjugated
产品编号 ABIN931387
发货至: 中国
  • 抗原 See all ERBB3 抗体
    ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
    抗原表位
    • 29
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    AA 1175-1275
    适用
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    宿主
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    小鼠
    克隆类型
    • 186
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    单克隆
    标记
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    This ERBB3 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    免疫原
    ERBB3 antibody was raised in Mouse using a purified recombinant fragment of ERBB3(aa1175-1275) expressed in E. coli as the immunogen.
    克隆位点
    3F10F6
    亚型
    IgG1
    Top Product
    Discover our top product ERBB3 Primary Antibody
  • 应用备注
    ELISA: 1:10,000, IHC: 1:200-1:1000, WB: 1:500-1:2000
    Optimal conditions should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Supplied as a liquid in ascitic fluid containing 0.03 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium Azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze/thaw cycles.
    Dilute only prior to immediate use.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C for short term storage. Store at -20 °C for long term storage.
  • 抗原
    ERBB3 (Receptor Tyrosine-Protein Kinase ErbB-3 (ERBB3))
    别名
    ERBB3 (ERBB3 产品)
    别名
    ErbB-3 antibody, HER3 antibody, LCCS2 antibody, MDA-BF-1 antibody, c-erbB-3 antibody, c-erbB3 antibody, erbB3-S antibody, p180-ErbB3 antibody, p45-sErbB3 antibody, p85-sErbB3 antibody, ERBB3 antibody, C76256 antibody, Erbb-3 antibody, Erbb3r antibody, Her3 antibody, nuc-ErbB3 antibody, erb-b2 receptor tyrosine kinase 3 antibody, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) antibody, ERBB3 antibody, Erbb3 antibody
    背景
    ERBB3 is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Synonyms: Monoclonal ERBB3 antibody, Anti-ERBB3 antibody, V-erb-b2 antibody, Erythroblastic leukemia viral oncogene homolog 3 antibody.
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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