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PC (C-Term) 抗体

适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN929285
发货至: 中国
  • 抗原
    PC
    抗原表位
    • 8
    • 6
    • 4
    • 2
    • 1
    • 1
    C-Term
    适用
    • 13
    • 9
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 17
    克隆类型
    • 17
    多克隆
    标记
    • 9
    • 2
    • 2
    • 2
    • 1
    • 1
    非结合性
    应用范围
    • 14
    • 12
    • 10
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Purified
    免疫原
    PC antibody was raised in rabbit using the C terminal of PC as the immunogen
  • 应用备注
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    PC Blocking Peptide, catalog no. 33R-8614, is also available for use as a blocking control in assays to test for specificity of this PC antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原
    PC
    背景
    This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. Synonyms: Polyclonal PC antibody, Anti-PC antibody, pyruvate carboxylase antibody, PCB antibody.
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