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PC (AA 53-82), (N-Term) 抗体

适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB31105 unconjugated
产品编号 ABIN656425
发货至: 中国
  • 抗原
    PC
    抗原表位
    • 7
    • 6
    • 4
    • 1
    • 1
    • 1
    AA 53-82, N-Term
    适用
    • 12
    • 9
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    小鼠
    宿主
    • 16
    克隆类型
    • 16
    多克隆
    标记
    • 8
    • 2
    • 2
    • 2
    • 1
    • 1
    非结合性
    应用范围
    • 13
    • 12
    • 10
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    This PC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-82 amino acids from the N-terminal region of human PC.
    预测反应
    Cow (Bovine),Rat (Rattus)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This PC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 53-82 AA from the N-terminal region of human PC.
    克隆位点
    RB31105
    亚型
    Ig Fraction
  • 应用备注
    WB = 1:1000, IHC (p) = 1:10-50
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    PBS with 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    PC Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    有效期
    6 months
  • 抗原
    PC
    背景
    This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene. [provided by RefSeq].
    Synonyms: Pyruvate carboxylase, mitochondrial,PC,
    分子量
    129634 DA
    基因ID
    5091
    NCBI登录号
    NP_000911, NP_001035806, NP_071504
    UniProt
    P11498
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