Caspase 10 抗体 (Middle Region)
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北京 101111
Quick Overview for Caspase 10 抗体 (Middle Region) (ABIN929111)
抗原
See all Caspase 10 (CASP10) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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纯化方法
- Purified
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免疫原
- CASP10 antibody was raised in rabbit using the middle region of CASP10 as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
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别名
- CASP10
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背景
- This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene. Synonyms: Polyclonal CASP10 antibody, Anti-CASP10 antibody, caspase 10, apoptosis-related cysteine peptidase antibody, ALPS2 antibody, FLICE2 antibody, MCH4 antibody.
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途径
- Apoptosis, Caspase Cascade in Apoptosis
抗原
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