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Caspase 10 抗体 (AA 430-479)

This 兔 多克隆 antibody specifically detects Caspase 10 in WB, ELISA, IHC 和 IF. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN1533218
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Caspase 10 抗体 (AA 430-479) (ABIN1533218)

抗原

See all Caspase 10 (CASP10) 抗体
Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

适用

人, 小鼠, 大鼠

宿主

  • 114
  • 4
  • 2
  • 1
兔

克隆类型

  • 88
  • 33
多克隆

标记

  • 48
  • 9
  • 5
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Caspase 10 antibody is un-conjugated

应用范围

  • 81
  • 55
  • 35
  • 33
  • 21
  • 21
  • 17
  • 14
  • 14
  • 8
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
  • 抗原表位

    • 16
    • 15
    • 12
    • 9
    • 8
    • 8
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 430-479

    原理

    Caspase-10 B/D Antibody

    特异性

    Caspase-10 B/D Polyclonal Antibody detects endogenous levels of proCaspase-10 B/D protein, actived Caspase-10 (isoform B and D) and Caspase-10(isoform B and D) subunit p12,

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    纯度

    > 95 %

    免疫原

    The antiserum was produced against synthesized peptide derived from human Caspase 10. AA range:430-479

    亚型

    IgG
  • 应用备注

    WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C/1 year

    有效期

    12 months
  • 抗原

    Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

    别名

    Caspase 10

    背景

    Synonyms: ALPS2, apoptotic protease Mch-4, CASP-10, CASPA, caspase-10, FADD-like ICE2, FAS-associated death domain protein interleukin-1B-convert

    Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011],

    Gene Name: CASP10

    Protein Name: Caspase10

    分子量

    58 kDa

    基因ID

    843, 4

    OMIM

    601762

    UniProt

    Q92851-2

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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