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UBA3 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects UBA3 in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 小鸡 和 非洲爪蟾.
产品编号 ABIN928369
发货至: 中国
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Quick Overview for UBA3 抗体 (N-Term) (ABIN928369)

抗原

See all UBA3 抗体
UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

适用

  • 28
  • 22
  • 13
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 斑马鱼, Cow, 犬, 小鸡, 非洲爪蟾

宿主

  • 29

克隆类型

  • 26
  • 3
多克隆

标记

  • 17
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This UBA3 antibody is un-conjugated

应用范围

  • 20
  • 13
  • 9
  • 3
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 抗原表位

    • 8
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    交叉反应

    小鼠, 大鼠, 牛, 犬, 小鸡, Frog, 斑马鱼

    纯化方法

    Purified

    免疫原

    UBA3 antibody was raised in rabbit using the N terminal of UBA3 as the immunogen
  • 应用备注

    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    UBA3 Blocking Peptide, (ABIN937832), is also available for use as a blocking control in assays to test for specificity of this UBA3 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    Lot specific

    缓冲液

    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原

    UBA3 (Ubiquitin-Like Modifier Activating Enzyme 3 (UBA3))

    别名

    UBA3

    背景

    UBA3 is a catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. UBA3 down-regulates steroid receptor activity. UBA3 is necessary for cell cycle progression.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. Synonyms: Polyclonal UBA3 antibody, Anti-UBA3 antibody, ubiquitin-like modifier activating enzyme 3 antibody, DKFZp566J164 antibody, MGC22384 antibody, UBE1C antibody, hUBA3 antibody.
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