Glucocorticoid Receptor 抗体 (N-Term)
Quick Overview for Glucocorticoid Receptor 抗体 (N-Term) (ABIN927317)
抗原
See all Glucocorticoid Receptor (NR3C1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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纯化方法
- Purified
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免疫原
- NR3 C1 antibody was raised in rabbit using the N terminal of NR3 1 as the immunogen
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应用备注
- Optimal conditions should be determined by the investigator.
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说明
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NR3C1 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this NR3C1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Glucocorticoid Receptor (NR3C1) (Nuclear Receptor Subfamily 3, Group C, Member 1 (Glucocorticoid Receptor) (NR3C1))
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别名
- NR3C1
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背景
- NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Synonyms: Polyclonal NR3C1 antibody, Anti-NR3C1 antibody, nuclear receptor subfamily 3, group C, member 1, glucocorticoid receptor antibody, GCCR antibody, GCR antibody, GR antibody, GRL antibody.
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途径
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Muscle Cell Differentiation, Regulation of Carbohydrate Metabolic Process
抗原
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