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Insulin Receptor 抗体 (Middle Region)

INSR 适用: 人, 小鼠, 大鼠, 犬, 兔, 斑马鱼, 非洲爪蟾 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN926933
发货至: 中国
  • 抗原 See all Insulin Receptor (INSR) 抗体
    Insulin Receptor (INSR)
    抗原表位
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    Middle Region
    适用
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    人, 小鼠, 大鼠, 犬, 兔, 斑马鱼, 非洲爪蟾
    宿主
    • 166
    • 23
    • 3
    • 1
    克隆类型
    • 158
    • 35
    多克隆
    标记
    • 118
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    This Insulin Receptor antibody is un-conjugated
    应用范围
    • 141
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    Western Blotting (WB), Immunohistochemistry (IHC)
    交叉反应
    小鼠, 大鼠, 犬, 兔, 斑马鱼, Frog
    纯化方法
    Purified
    免疫原
    INSR antibody was raised in rabbit using the middle region of INSR as the immunogen
    Top Product
    Discover our top product INSR Primary Antibody
  • 应用备注
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    INSR Blocking Peptide, catalog no. 33R-8809, is also available for use as a blocking control in assays to test for specificity of this INSR antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原
    Insulin Receptor (INSR)
    别名
    INSR (INSR 产品)
    别名
    CD220 antibody, HHF5 antibody, 4932439J01Rik antibody, D630014A15Rik antibody, IR antibody, IR-A antibody, IR-B antibody, 18402 antibody, CG18402 antibody, DIHR antibody, DILR antibody, DIR antibody, DIRH antibody, DIRbeta antibody, DInR antibody, DInr antibody, Dir-a antibody, Dir-b antibody, Dmel\\CG18402 antibody, INR antibody, INS antibody, Inr antibody, Inr-alpha antibody, Inr-beta antibody, InsR antibody, dINR antibody, dIR antibody, dIRH antibody, dInR antibody, dInr antibody, dInsR antibody, dinr antibody, dir antibody, er10 antibody, inr antibody, insulin/insulin-like growth factor receptor antibody, l(3)05545 antibody, l(3)93Dj antibody, l(3)er10 antibody, lnR antibody, ir-A antibody, CTK-1 antibody, ir antibody, INSR antibody, NV14476 antibody, cd220 antibody, hhf5 antibody, insulin receptor antibody, Insulin-like receptor antibody, insulin receptor L homeolog antibody, INSR antibody, Insr antibody, InR antibody, LOC100122567 antibody, LOC100451802 antibody, insr.L antibody
    背景
    This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. INSR mediates the metabolic functions of insulin. INSR binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). INSR can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1. When present in a hybrid receptor with IGF1R, it binds IGF1. Synonyms: Polyclonal INSR antibody, Anti-INSR antibody, insulin receptor antibody, CD220 antibody, HHF5 antibody.
    途径
    NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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