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Insulin Receptor 抗体 (Middle Region)

The 兔 多克隆 anti-Insulin Receptor antibody is suitable to detect Insulin Receptor in samples from 人, 小鼠, 大鼠, 犬, 兔, 斑马鱼 和 非洲爪蟾. It has been validated for WB 和 IHC.
产品编号 ABIN926933
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Insulin Receptor 抗体 (Middle Region) (ABIN926933)

抗原

See all Insulin Receptor (INSR) 抗体
Insulin Receptor (INSR)

适用

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人, 小鼠, 大鼠, 犬, 兔, 斑马鱼, 非洲爪蟾

宿主

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克隆类型

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多克隆

标记

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This Insulin Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    Middle Region

    交叉反应

    小鼠, 大鼠, 犬, 兔, 斑马鱼, Frog

    纯化方法

    Purified

    免疫原

    INSR antibody was raised in rabbit using the middle region of INSR as the immunogen
  • 应用备注

    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    INSR Blocking Peptide, (ABIN5614204), is also available for use as a blocking control in assays to test for specificity of this INSR antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    Lot specific

    缓冲液

    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原

    Insulin Receptor (INSR)

    别名

    INSR

    背景

    This receptor binds insulin and has a tyrosine-protein kinase activity. Isoform Short has a higher affinity for insulin. INSR mediates the metabolic functions of insulin. INSR binding to insulin stimulates association of the receptor with downstream mediators including IRS1 and phosphatidylinositol 3'-kinase (PI3K). INSR can activate PI3K either directly by binding to the p85 regulatory subunit, or indirectly via IRS1. When present in a hybrid receptor with IGF1R, it binds IGF1. Synonyms: Polyclonal INSR antibody, Anti-INSR antibody, insulin receptor antibody, CD220 antibody, HHF5 antibody.

    途径

    NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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