E2F1 抗体 (C-Term)
Quick Overview for E2F1 抗体 (C-Term) (ABIN926914)
抗原
See all E2F1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 小鼠, 牛, 犬
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纯化方法
- Purified
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免疫原
- E2 F1 antibody was raised in rabbit using the C terminal of E2 1 as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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E2F1 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this E2F1 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- E2F1 (E2F Transcription Factor 1 (E2F1))
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别名
- E2F1
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背景
- The protein encoded by E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. Synonyms: Polyclonal E2F1 antibody, Anti-E2F1 antibody, E2F transcription factor 1 antibody.
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途径
- p53 Pathway, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy
抗原
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