Cyclin D3 抗体 (C-Term)
Quick Overview for Cyclin D3 抗体 (C-Term) (ABIN926905)
抗原
See all Cyclin D3 (CCND3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 小鼠, 大鼠, 犬, 牛, 猪, 小鸡
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纯化方法
- Purified
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免疫原
- CCND3 antibody was raised in rabbit using the C terminal of CCND3 as the immunogen
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应用备注
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WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. -
说明
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CCND3 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this CCND3 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Cyclin D3 (CCND3)
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别名
- CCND3
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背景
- CCND3 encodes a protein that belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Synonyms: Polyclonal CCND3 antibody, Anti-CCND3 antibody, cyclin D3 antibody.
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途径
- Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
抗原
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