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KPNB1 抗体 (N-Term)

This anti-KPNB1 antibody is a 兔 多克隆 antibody detecting KPNB1 in WB. Suitable for 人.
产品编号 ABIN926686
发货至: 中国

Quick Overview for KPNB1 抗体 (N-Term) (ABIN926686)

抗原

See all KPNB1 抗体
KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

适用

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宿主

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克隆类型

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多克隆

标记

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This KPNB1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    N-Term

    纯化方法

    Purified

    免疫原

    KPNB1 antibody was raised in rabbit using the N terminal of KPNB1 as the immunogen
  • 应用备注

    Optimal conditions should be determined by the investigator.

    说明

    KPNB1 Blocking Peptide, (ABIN937840), is also available for use as a blocking control in assays to test for specificity of this KPNB1 antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    Lot specific

    缓冲液

    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原

    KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))

    别名

    KPNB1

    背景

    Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family. Synonyms: Polyclonal KPNB1 antibody, Anti-KPNB1 antibody, karyopherin, importin beta 1 antibody, IMB1 antibody, IPO1 antibody, IPOB antibody, Impnb antibody, MGC2155 antibody, MGC2156 antibody, MGC2157 antibody, NTF97 antibody.

    途径

    Protein targeting to Nucleus
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