MAPK14 抗体 (C-Term)
Quick Overview for MAPK14 抗体 (C-Term) (ABIN926006)
抗原
See all MAPK14 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应
- 小鼠, 大鼠, 犬
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免疫原
- MAPK14 antibody was raised in rabbit using the C terminal of MAPK14 as the immunogen
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应用备注
- Optimal conditions should be determined by the investigator.
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说明
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MAPK14 Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this MAPK14 antibody
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限制
- 仅限研究用
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状态
- Lyophilized
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浓度
- Lot specific
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缓冲液
- Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
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注意事项
- Avoid repeated freeze/thaw cycles.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))
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别名
- MAPK14
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背景
- MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Synonyms: Polyclonal MAPK14 antibody, Anti-MAPK14 antibody, mitogen-activated protein kinase 14 antibody.
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途径
- MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins
抗原
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