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Topoisomerase II alpha 抗体 (C-Term)

This 兔 多克隆 anti-Topoisomerase II alpha antibody specifically detects Topoisomerase II alpha in WB. The antibody is reactive with 人, 小鼠, 大鼠, Pig 和 犬 samples.
产品编号 ABIN926005
发货至: 中国
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Quick Overview for Topoisomerase II alpha 抗体 (C-Term) (ABIN926005)

抗原

See all Topoisomerase II alpha (TOP2A) 抗体
Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

适用

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人, 小鼠, 大鼠, Pig, 犬

宿主

  • 118
  • 39

克隆类型

  • 94
  • 63
多克隆

标记

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This Topoisomerase II alpha antibody is un-conjugated

应用范围

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  • 1
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Western Blotting (WB)
  • 抗原表位

    • 19
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    • 1
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    C-Term

    交叉反应

    犬, 大鼠, 小鼠, 猪

    免疫原

    TOP2 A antibody was raised in rabbit using the C terminal of TOP2 as the immunogen
  • 应用备注

    WB: 1.25 µg/mL
    Optimal conditions should be determined by the investigator.

    说明

    TOP2A Blocking Peptide, , is also available for use as a blocking control in assays to test for specificity of this TOP2A antibody

    限制

    仅限研究用
  • 状态

    Lyophilized

    浓度

    Lot specific

    缓冲液

    Lyophilized powder. Add 100 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

    注意事项

    Avoid repeated freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原

    Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))

    别名

    TOP2A

    背景

    TOP2A is a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. The gene encoding this form, alpha, is localized to chromsome 17 and the beta gene is localized to chromosome 3. Synonyms: Polyclonal TOP2A antibody, Anti-TOP2A antibody, topoisomerase, DNA II alpha 170kDa antibody.

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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