MAS1 抗体 (AbBy Fluor® 555)
Quick Overview for MAS1 抗体 (AbBy Fluor® 555) (ABIN905733)
抗原
See all MAS1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 人, 小鼠
-
预测反应
- Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit,Guinea Pig
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human MAS1
-
亚型
- IgG
-
-
-
-
应用备注
-
FCM 1:20-100
IF(IHC-P) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- MAS1 (MAS1 Oncogene (MAS1))
-
别名
- Mas1
-
背景
-
Synonyms: MAS, MGRA, Proto-oncogene Mas, MAS1
Background: Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.
-
基因ID
- 4142
-
UniProt
- P04201
-
途径
- ACE Inhibitor Pathway, Regulation of Carbohydrate Metabolic Process
抗原
-