INSRR 抗体 (PE)
Quick Overview for INSRR 抗体 (PE) (ABIN902841)
抗原
See all INSRR 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Excitation / Emission Wavelengths: 565nm/578nm
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交叉反应
- 大鼠, 犬, 猪, 牛
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纯化方法
- purified by Protein A
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免疫原
- KLH conjugated synthetic peptide derived from human Insulin receptor-related protein beta chain
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亚型
- IgG
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说明
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Excitation / Emission wavelength: 496nm / 578nm
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 µg/µL
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缓冲液
- Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store at 4 °C for 12 months
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有效期
- 12 months
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- INSRR (Insulin Receptor-Related Receptor (INSRR))
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别名
- INSRR
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背景
- The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor composed of two alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Member of the insulin RTK family, IRR shares high homology with the insulin (IR) and the insulin-like growth factor-1 receptor (IGF-1R), but doesnメt bind any of IR and IGF-1R known ligands. In contrast to the widespread patterns of expression to IR and IGF-1R, IRR demonstrates a very restricted cellular distribution in a subset of tissues of neuronal origin and its biological functions are still unknown.
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分子量
- 144kDa
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基因ID
- 3645
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途径
- RTK signaling
抗原
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