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IKZF1 抗体 (AA 251-360) (Cy5.5)

This anti-IKZF1 antibody is a 兔 多克隆 antibody detecting IKZF1 in WB, IF (cc) 和 IF (p). Suitable for 小鼠.
产品编号 ABIN901995
发货至: 中国

Quick Overview for IKZF1 抗体 (AA 251-360) (Cy5.5) (ABIN901995)

抗原

See all IKZF1 抗体
IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

适用

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小鼠

宿主

  • 59
  • 12
  • 2

克隆类型

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  • 16
多克隆

标记

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This IKZF1 antibody is conjugated to Cy5.5

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 251-360

    交叉反应

    小鼠

    预测反应

    Human,Rat,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human IKAROS

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    IKZF1 (IKAROS Family Zinc Finger 1 (Ikaros) (IKZF1))

    别名

    IKAROS

    背景

    Synonyms: IKAROS family zinc finger 1 Ikaros, PRO0758, CLL associated antigen KW 6, DNA-binding protein Ikaros, hIk 1, hIk-1, IK1, Ikaros zinc finger protein, IKAROS, Ikaros family zinc finger protein 1, Ikzf1, IKZF1_HUMAN, LYF1, Lymphoid transcription factor LyF-1, zinc finger protein subfamily 1A 1, ZNFN1A1.

    Background: Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs).Tissue specificity:Abundantly expressed in thymus, spleen and peripheral blood Leukocytes and lymph nodes. Lower expression in bone marrow and small intestine.

    基因ID

    10320

    途径

    Production of Molecular Mediator of Immune Response
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