Calpain 2 抗体 (AA 301-400) (AbBy Fluor® 350)
Quick Overview for Calpain 2 抗体 (AA 301-400) (AbBy Fluor® 350) (ABIN886194)
抗原
See all Calpain 2 (CAPN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 301-400
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Dog,Cow,Sheep
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from mouse Calpain 2
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亚型
- IgG
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anti-Calpain 2 (CAPN2) (AA 20-700), (Catalytic Subunit) antibody
CAPN2 适用: 人 WB, ELISA, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Calpain 2 (CAPN2) (AA 45-514) antibodyCAPN2 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 2 (CAPN2) (AA 1-400) antibodyCAPN2 适用: 人 WB, IHC (p), FACS 宿主: 小鼠 Monoclonal 1381CT669-7-66-71 unconjugated
anti-Calpain 2 (CAPN2) (AA 350-680) antibodyCAPN2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calpain 2 (CAPN2) (AA 489-700) antibodyCAPN2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2E2F2 unconjugated
anti-Calpain 2 (CAPN2) (AA 500-700) antibodyCAPN2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Calpain 2 (CAPN2) antibodyCAPN2 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 小鼠 Monoclonal 1C1 unconjugated
anti-Calpain 2 (CAPN2) (AA 301-335) antibodyCAPN2 适用: 人 WB 宿主: 兔 Polyclonal RB52877 unconjugated
anti-Calpain 2 (CAPN2) (AA 1-700) antibodyCAPN2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Calpain 2 (CAPN2) antibodyCAPN2 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Calpain 2 (CAPN2)
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别名
- Calpain 2
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背景
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Synonyms: Calcium activated neutral proteinase 2, Calcium activated neutral proteinase, CALP80, Calpain 2 m/II large subunit, Calpain 2 catalytic subunit, Calpain 2 large catalytic subunit, Calpain 2 large subunit, Calpain large polypeptide L2, Calpain M type, Calcium-activated neutral proteinase 2, CALP80, Calpain 2, large [catalytic] subunit, Calpain M-type, Calpain-2 catalytic subunit, Calpain-2 large subunit, CAN2_MOUSE, M-calpain, Millimolar-calpain, Calpain2, CANP 2, CANP L2, CANP2, CANPL 2, CANPL2, CANPml, Capa2, CAPN 2, CAPN2, FLJ39928, M calpain, M calpin, M type, mCANP, Millimolar calpain.
Background: Calpain, and m calpain, also known as Calpain 2, are intracellular, calcium dependent cysteine proteases. Mu calpain has a micromolar sensitivity (thus the mu) as compared to the millimolar calcium sensitivity of m calpain. Both Calpains 1 and 2 are composed of an 80 kD subunit and a 30 kD subunit. Whereas the 30 kDa subunit is shared by both enzymes, the larger catalytic subunits are different and exhibit the distinct Ca++ requirements that are suggested by their names. The calpains have papain like activity, thus the pain nomenclature. Both Calpain 1 and Calpain 2 are ubiquitously expressed, and are countered by the endogenous calpain inhibitor, calpastatin. Other calpain family members (calpain 94, ncl2, ncl3, etc) have more limited tissue distribution, and perhaps different functions. The calpain family members consist of a common small subunit (Calpain 4), and a large variable subunit. It is not clear that all calpains contain a small subunit. Domains in the large subunit include the amino terminal domain I, the proteinase domain II, domain III, and the EF hand domain IV. The calpains appear to serve multiple physiological roles, and ideas concerning the functions of these enzymes are in a state of rapid flux.
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基因ID
- 824
抗原
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