ACVR1C/ALK7 抗体 (AA 21-120) (AbBy Fluor® 350)
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北京 101111
Quick Overview for ACVR1C/ALK7 抗体 (AA 21-120) (AbBy Fluor® 350) (ABIN881211)
抗原
See all ACVR1C/ALK7 (ACVR1C) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-120
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ACTRIC/Activin A Receptor Type IC
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亚型
- IgG
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
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别名
- Activin A Receptor Type IC
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背景
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Synonyms: ALK7, ACVRLK7, Activin receptor type-1C, Activin receptor type IC, ACTR-IC, Activin receptor-like kinase 7, ALK-7, ACVR1C
Background: Serine/threonine protein kinase which forms a receptor complex on ligand binding. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3. Receptor for activin AB, activin B and NODAL. Plays a role in cell differentiation, growth arrest and apoptosis.
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基因ID
- 130399
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UniProt
- Q8NER5
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途径
- Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity
抗原
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