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FAK 抗体 (pTyr407) (AbBy Fluor® 555)

PTK2 适用: 人, 小鼠 WB, IF (p), IF (cc), FACS 宿主: 兔 Polyclonal AbBy Fluor® 555
产品编号 ABIN879655
发货至: 中国
  • 抗原 See all FAK (PTK2) 抗体
    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
    抗原表位
    • 43
    • 33
    • 30
    • 28
    • 23
    • 22
    • 21
    • 18
    • 16
    • 16
    • 13
    • 11
    • 7
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    • 5
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    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
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    • 2
    • 2
    • 2
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    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr407
    适用
    • 326
    • 273
    • 205
    • 21
    • 21
    • 17
    • 16
    • 11
    • 8
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 335
    • 15
    • 3
    • 2
    • 1
    • 1
    克隆类型
    • 329
    • 28
    多克隆
    标记
    • 156
    • 17
    • 16
    • 12
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
    • 10
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    • 9
    • 6
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    • 6
    • 1
    • 1
    This FAK antibody is conjugated to AbBy Fluor® 555
    应用范围
    • 289
    • 132
    • 132
    • 119
    • 106
    • 68
    • 60
    • 42
    • 31
    • 28
    • 23
    • 5
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)
    交叉反应
    人, 小鼠
    预测反应
    Rat,Dog,Cow,Sheep,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human FAK around the phosphorylation site of Tyr407
    亚型
    IgG
    Top Product
    Discover our top product PTK2 Primary Antibody
  • 应用备注
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    FAK (PTK2) (PTK2 Protein tyrosine Kinase 2 (PTK2))
    别名
    FAK (PTK2 产品)
    背景

    Synonyms: FAK phospho Y407, p-FAK phospho Y407, FADK 1, FADK, FAK 1, FAK related non kinase polypeptide, FAK1, Focal adhesion kinase 1, FRNK, pp125FAK, Protein tyrosine kinase 2, Protein Tyrosine Kinase Cytoplasmic, PTK 2, FAK1_HUMAN, Focal adhesion kinase-related nonkinase, Protein phosphatase 1 regulatory subunit 71, PPP1R71, Protein-tyrosine kinase 2, p125FAK.

    Background: Non-receptor protein-tyrosine kinase implicated in signaling pathways involved in cell motility, proliferation and apoptosis. Activated by tyrosine-phosphorylation in response to either integrin clustering induced by cell adhesion or antibody cross-linking, or via G-protein coupled receptor (GPCR) occupancy by ligands such as bombesin or lysophosphatidic acid, or via LDL receptor occupancy. Plays a potential role in oncogenic transformations resulting in increased kinase activity. [SUBCELLULAR LOCATION] Cell junction, focal adhesion. Cell membrane, Peripheral membrane protein, Cytoplasmic side. Note=Constituent of focal adhesions.

    基因ID
    5747
    UniProt
    Q05397
    途径
    Response to Growth Hormone Stimulus, CXCR4-mediated Signaling Events, Smooth Muscle Cell Migration, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling
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