E2F1 抗体 (pSer337) (AbBy Fluor® 488)
Quick Overview for E2F1 抗体 (pSer337) (AbBy Fluor® 488) (ABIN875622)
抗原
See all E2F1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer337
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交叉反应
- 小鼠
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预测反应
- Human,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human E2F1 around the phosphorylation site of Ser337
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亚型
- IgG
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anti-E2F Transcription Factor 1 (E2F1) (AA 69-223) antibody
E2F1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 8G9 unconjugated
anti-E2F Transcription Factor 1 (E2F1) antibodyE2F1 适用: 人 WB, ELISA, IHC, FACS, IF 宿主: 兔 Monoclonal 1D12 unconjugated Recombinant Antibody
anti-E2F Transcription Factor 1 (E2F1) (AA 348-437) antibodyE2F1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-E2F Transcription Factor 1 (E2F1) (AA 101-180) antibodyE2F1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (p), IF (cc), FACS, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (AA 133-362) antibodyE2F1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) antibodyE2F1 适用: 人 WB, IP, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (AA 342-371) antibodyE2F1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (pSer364) antibodyE2F1 适用: 人 WB, ELISA, IF (p), IF (cc), FACS, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (pThr433) antibodyE2F1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-E2F Transcription Factor 1 (E2F1) (C-Term) antibodyE2F1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- E2F1 (E2F Transcription Factor 1 (E2F1))
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别名
- E2F1
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背景
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Synonyms: E2F1Ser337, p-E2F1 Ser337, E2F1 phospho S337, E2F 1, E2F transcription factor 1, E2F-1, E2f1 E2F transcription factor 1, KIAA4009, mKIAA4009, OTTHUMP00000030661, PBR 3, PBR3, PRB binding protein E2F 1, PRB-binding protein E2F-1, RBAP 1, RBAP-1, RBAP1, RBBP 3, RBBP-3, RBBP3, RBP 3, RBP3, Retinoblastoma associated protein 1, Retinoblastoma binding protein 3, Retinoblastoma-associated protein 1, Retinoblastoma-binding protein 3, Transcription factor E2F1, E2F1_HUMAN.
Background: E2F's are DNA binding proteins, which associate with negative regulators, such as the retinoblastoma p107 protein, resulting in an altered rate of gene transcription. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. E2F1 is proposed to be involved in several cellular processes that range from tumor suppressor, cell progression and oncogenesis. E2F1 overexpression can also drive cells into apoptosis.
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基因ID
- 1869
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UniProt
- Q01094
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途径
- p53 Pathway, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy
抗原
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