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ALOX5 抗体 (pSer271) (AbBy Fluor® 350)

This anti-ALOX5 antibody is a 兔 多克隆 antibody detecting ALOX5 in IF (cc) 和 IF (p). Suitable for 大鼠.
产品编号 ABIN875251
发货至: 中国

Quick Overview for ALOX5 抗体 (pSer271) (AbBy Fluor® 350) (ABIN875251)

抗原

See all ALOX5 抗体
ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This ALOX5 antibody is conjugated to AbBy Fluor® 350

应用范围

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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    pSer271

    交叉反应

    大鼠

    预测反应

    Human,Mouse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from rat 5-Lipoxygenase around the phosphorylation site of Ser271

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

    别名

    5-Lipoxygenase

    背景

    Synonyms: 5-lipoxygenase, 5 LO, 5LPG, ALOX 5, ALOX5, Arachidonate 5 lipoxygenase, Arachidonic acid 5 lipoxygenase, Leukotriene A4 synthase, LOG 5, LOG5, MGC163204, LOX5_HUMAN.

    Background: This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

    基因ID

    240
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