CCDC98 抗体 (AA 51-150)
Quick Overview for CCDC98 抗体 (AA 51-150) (ABIN872878)
抗原
See all CCDC98 (FAM175A) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 51-150
-
交叉反应
- 小鼠
-
预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human CCDC98
-
亚型
- IgG
-
-
anti-Family with Sequence Similarity 175, Member A (FAM175A) (AA 1-313) antibody
FAM175A 适用: 人 WB, IP, ICFC 宿主: 小鼠 Monoclonal ABRA1-01 unconjugated
anti-Family with Sequence Similarity 175, Member A (FAM175A) (AA 350-400) antibodyFAM175A 适用: 人 WB, IP, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 175, Member A (FAM175A) (N-Term) antibodyFAM175A 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
-
别名
- CCDC98
-
背景
-
Synonyms: ABRA1, CCDC98, BRCA1-A complex subunit Abraxas, Coiled-coil domain-containing protein 98, Protein FAM175A, FAM175A, UNQ496/PRO1013
Background: Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.
-
基因ID
- 84142
-
UniProt
- Q6UWZ7
-
途径
- DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
抗原
-
