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INSRR 抗体 (AA 801-900)

This anti-INSRR antibody is a 兔 多克隆 antibody detecting INSRR in ELISA, IHC (p), IF (p), IF (cc) 和 IHC (fro). Suitable for 人.
产品编号 ABIN872418
发货至: 中国

Quick Overview for INSRR 抗体 (AA 801-900) (ABIN872418)

抗原

See all INSRR 抗体
INSRR (Insulin Receptor-Related Receptor (INSRR))

适用

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宿主

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克隆类型

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多克隆

标记

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This INSRR antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    AA 801-900

    交叉反应

    预测反应

    Mouse,Rat,Dog,Cow,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Insulin receptor-related protein beta chain

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    INSRR (Insulin Receptor-Related Receptor (INSRR))

    别名

    INSRR

    背景

    Synonyms: INSRR, Insulin receptor related receptor precursor, IR related receptor, IRR, Sirr, Insulin receptor-related protein, IR-related receptor, Insulin receptor-related protein beta chain, INSRR_HUMAN.

    Background: The insulin receptor related receptor (IRR) is a heterotetrameric transmembrane receptor composed of two alpha and 2 beta chains linked by disulfide bonds. The alpha chains contribute to the formation of the ligand-binding domain, while the beta chains carry the kinase domain. Member of the insulin RTK family, IRR shares high homology with the insulin (IR) and the insulin-like growth factor-1 receptor (IGF-1R), but doesn?t bind any of IR and IGF-1R known ligands. In contrast to the widespread patterns of expression to IR and IGF-1R, IRR demonstrates a very restricted cellular distribution in a subset of tissues of neuronal origin and its biological functions are still unknown.

    基因ID

    3645

    途径

    RTK signaling
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