PKM1 (AA 399-403) 抗体
(2 references)Quick Overview for PKM1 (AA 399-403) 抗体 (ABIN871702)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 399-403
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特异性
- The antibody detects endogenous levels of total PKM1 protein.
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纯化方法
- Affinity purified
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免疫原
- Peptide sequence around AA 399-403 (V-R-A-S-S) derived from Human PKM1. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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anti-PKM1 (AA 383-417), (C-Term) antibody
适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB18404 unconjugated
anti-PKM1 antibody适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-PKM1 antibody适用: 人 WB 宿主: 小鼠 Monoclonal OTI3C6 unconjugated
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应用备注
- Western blotting: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- PKM1
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背景
- Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival.
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分子量
- 60 kDa
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基因ID
- 5315
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NCBI登录号
- NP_872270
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UniProt
- P14618
抗原
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