CD44 抗体 (AA 734-738)
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Quick Overview for CD44 抗体 (AA 734-738) (ABIN871672)
抗原
See all CD44 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 734-738
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特异性
- The antibody detects endogenous level of total CD44 protein.
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纯化方法
- Affinity purified
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免疫原
- Peptide sequence around AA 734-738 (Q-N-V-D-M) derived from Human CD44. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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应用备注
- Western blotting: 1:500-1:1000
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
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- CD44
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别名
- CD44
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背景
- Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.
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分子量
- 80 kDa
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基因ID
- 960
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NCBI登录号
- NP_000601
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UniProt
- P16070
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途径
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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