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CD44 抗体 (AA 734-738)

This 兔 多克隆 antibody specifically detects CD44 in WB. It exhibits reactivity toward 人 和 大鼠.
产品编号 ABIN871672
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CD44 抗体 (AA 734-738) (ABIN871672)

抗原

See all CD44 抗体
CD44

适用

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人, 大鼠

宿主

  • 229
  • 177
  • 94
  • 11
  • 1

克隆类型

  • 391
  • 114
  • 4
多克隆

标记

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This CD44 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 734-738

    特异性

    The antibody detects endogenous level of total CD44 protein.

    纯化方法

    Affinity purified

    免疫原

    Peptide sequence around AA 734-738 (Q-N-V-D-M) derived from Human CD44. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
  • 应用备注

    Western blotting: 1:500-1:1000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原

    CD44

    别名

    CD44

    背景

    Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

    分子量

    80 kDa

    基因ID

    960

    NCBI登录号

    NP_000601

    UniProt

    P16070

    途径

    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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