EGFR 抗体 (C-Term)
Quick Overview for EGFR 抗体 (C-Term) (ABIN870533)
抗原
See all EGFR 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 1120-1135, C-Term
-
原理
- Anti-EGFR
-
特异性
- EGFR
-
免疫原
- Peptide derived from C-terminal region of human epidermal growth factor receptor (EGFR). Antibody recognizes the epitope between Ser1120 - Asn1135.
-
亚型
- IgG
-
-
-
-
应用备注
- 1:100 - 200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/mL BSA, Preservative: 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- +2 °C to +8 °C
-
-
- EGFR (Epidermal Growth Factor Receptor (EGFR))
-
别名
- EGFR
-
背景
- Epidermal Growth Factor Receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR overexpression in tumors indicates poor prognosis and is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, colon and in squamous cell carcinoma.
-
UniProt
- P00533
-
途径
- NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins
抗原
-