MUC1 抗体 (C-Term)
Quick Overview for MUC1 抗体 (C-Term) (ABIN870416)
抗原
See all MUC1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1235-1253, C-Term
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原理
- Anti-EMA (CD227, Mucin-1)
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特异性
- EMA (CD227, Mucin
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免疫原
- Peptide derived from C-terminal sequence of human Mucin-1. Antibody recognizes the epitope between Gly1235 - Ala1253.
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亚型
- IgG
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应用备注
- IHC-P 1:100 - 200, IHC-Fr 1:400-600
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/mL BSA, Preservative: 0.05 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- +2 °C to +8 °C
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- MUC1 (Mucin 1 (MUC1))
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别名
- EMA
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背景
- Anti-EMA antibody is a useful marker for staining several types of carcinomas. It stains normal and neoplastic cells from various tissues, including mammary epithelium, sweat glands and squamous epithelium. Hepatocellular carcinoma, adrenal carcinoma and embryonal carcinomas are consistently EMA negative, so keratin positivity with negative EMA favors one of these tumors. EMA is frequently positive in meningiomas, breast, ovary, lung and prostate tumors.
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UniProt
- P15941
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途径
- Negative Regulation of intrinsic apoptotic Signaling
抗原
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