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Cyclin D3 抗体

The 小鼠 单克隆 anti-Cyclin D3 antibody (Clone 6H4) (ABIN865425) specifically detects Cyclin D3 in WB 和 ELISA. The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN865425
发货至: 中国
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Quick Overview for Cyclin D3 抗体 (ABIN865425)

抗原

See all Cyclin D3 (CCND3) 抗体
Cyclin D3 (CCND3)

适用

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人, 小鼠

宿主

  • 100
  • 15
小鼠

克隆类型

  • 79
  • 36
单克隆

标记

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This Cyclin D3 antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA

克隆位点

6H4
  • 纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human CCND3 expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    WB: 1/500 - 1/2000, ELISA: Propose dilution 1/10000.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100g/100l

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • 抗原

    Cyclin D3 (CCND3)

    别名

    CCND3

    背景

    The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation. Several transcript variants encoding different isoforms have been found for this gene. Synonyms: CCND3

    分子量

    32kDa

    基因ID

    896

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases, Glycosaminoglycan Metabolic Process
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