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Integrin beta 3 抗体

Name: Integrin beta 3 抗体
Brand: antibodies-online
SKU: ABIN810075
Availability: OutOfStock

Cited in 6+ publications. This anti-Integrin beta 3 antibody is a 小鼠单克隆 antibody detecting Integrin beta 3 in WB, FACS 和 IHC (fro). Suitable for 人和 Non-Human Primate.

Flow cytometry surface staining pattern of human peripheral whole blood stained using anti-human CD61 (VIPL2) purified antibody (concentration in sample 3 μg/mL, GAM APC). (Integrin beta 3 抗体)

FACS

Separation of human CD61 positive thrombocytes (red-filled) from neutrophil granulocytes (black-dashed) in flow cytometry analysis (surface staining) of peripheral whole blood stained using anti-human CD61 (VIPL2) purified antibody (concentration in sample 3 μg/mL, GAM APC). (Integrin beta 3 抗体)

FACS

2 images

(6 references)

产品编号 ABIN810075

发货至: 中国

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Quick Overview for Integrin beta 3 抗体 (ABIN810075)

抗原

See all Integrin beta 3 (ITGB3) 抗体

Integrin beta 3 (ITGB3)

适用

人, Non-Human Primate

宿主

小鼠

克隆类型

单克隆

标记

This Integrin beta 3 antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

克隆位点

VIPL2

Discover our top product ITGB3 Primary Antibody

原理

Anti-Hu CD61 Purified

特异性

The mouse monoclonal antibody VIPL2 recognizes an extracellular epitope of CD61, a 90-110 kDa transmembrane glycoprotein of integrin family, expressed on platelets, megacaryocytes, osteoclasts, endothelial cells and other cell types, including leucocytes and smooth muscle cells.

交叉反应（详细）

Human, Non-Human Primates

纯化方法

Purified by protein-A affinity chromatography.

纯度

> 95 % (by SDS-PAGE)

亚型

IgG1 kappa
anti-Integrin beta 3 (ITGB3) (AA 27-120) antibody
ITGB3 适用: 人, 小鼠 WB, FACS, ELISA, IHC (fro), IHC (p), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) (AA 134-376) antibody
ITGB3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) antibody
ITGB3 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated

anti-Integrin beta 3 (ITGB3) (AA 27-179) antibody
ITGB3 适用: 人 IHC, FACS, ELISA 宿主: 小鼠 Monoclonal 3E8A6 unconjugated

anti-Integrin beta 3 (ITGB3) (AA 610-718) antibody
ITGB3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) (AA 385-490) antibody
ITGB3 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ITGB3-2145 unconjugated

anti-Integrin beta 3 (ITGB3) antibody (FITC)
ITGB3 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal VIPL2 FITC

anti-Integrin beta 3 (ITGB3) antibody (PerCP)
ITGB3 适用: 人, Non-Human Primate FACS 宿主: 小鼠 Monoclonal VIPL2 PerCP

anti-Integrin beta 3 (ITGB3) (AA 734-760) antibody
ITGB3 适用: 人 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Integrin beta 3 (ITGB3) (AA 135-377) antibody
ITGB3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Flow cytometry: Recommended dilution: 1-4 μg/mL.

限制

仅限研究用
浓度

1 mg/mL

缓冲液

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Do not freeze.

储存条件

4 °C

储存方法

Store at 2-8°C. Do not freeze.
Barrett, Dai, Gamberg, Gallant, Grant: "Circulating CD14-CD36+ peripheral blood mononuclear cells constitutively produce interleukin-10." in: Journal of leukocyte biology, Vol. 82, Issue 1, pp. 152-60, (2007) (PubMed).

Mondal, Williams, Ali, Eilers, Agrawal: "The HIV-1 Tat protein selectively enhances CXCR4 and inhibits CCR5 expression in megakaryocytic K562 cells." in: Experimental biology and medicine (Maywood, N.J.), Vol. 230, Issue 9, pp. 631-44, (2005) (PubMed).

Williams, Mondal, Agrawal: "The HIV-1 Tat protein enhances megakaryocytic commitment of K562 cells by facilitating CREB transcription factor coactivation by CBP." in: Experimental biology and medicine (Maywood, N.J.), Vol. 230, Issue 11, pp. 872-84, (2005) (PubMed).

Roberts, Woods, Dale, Van Der Sluijs, Norman: "Protein kinase B/Akt acts via glycogen synthase kinase 3 to regulate recycling of alpha v beta 3 and alpha 5 beta 1 integrins." in: Molecular and cellular biology, Vol. 24, Issue 4, pp. 1505-15, (2004) (PubMed).

Ciarlet, Crawford, Cheng, Blutt, Rice, Bergelson, Estes: "VLA-2 (alpha2beta1) integrin promotes rotavirus entry into cells but is not necessary for rotavirus attachment." in: Journal of virology, Vol. 76, Issue 3, pp. 1109-23, (2002) (PubMed).

Dzionek, Fuchs, Schmidt, Cremer, Zysk, Miltenyi, Buck, Schmitz: "BDCA-2, BDCA-3, and BDCA-4: three markers for distinct subsets of dendritic cells in human peripheral blood." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 11, pp. 6037-46, (2000) (PubMed).
抗原

Integrin beta 3 (ITGB3)

别名

CD61

背景

Integrin subunit beta 3,CD61 (beta3 integrin) is a transmembrane glycoprotein, which associates with CD41 or CD51 Molecules to form heterodimeric adhesion receptores. CD41/CD61 complex is one of the earliest markers of the megakaryocytic lineage. It binds to fibronectin, fibrinogen and von Willebrand factor, and is involved in platelet aggregation. CD51/CD61 complex has similar binding properties and is involved in modulating migration and survival of angiogenic endothelial cells.,integrin beta 3, ITGB3, GP3A

基因ID

3690

UniProt

P05106

途径

Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Integrin Complex

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