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ASK1 抗体 (pSer1033) (Cy7)

MAP3K5 适用: 兔 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy7
产品编号 ABIN802059
发货至: 中国
  • 抗原 See all ASK1 (MAP3K5) 抗体
    ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
    抗原表位
    • 26
    • 26
    • 17
    • 16
    • 16
    • 12
    • 12
    • 9
    • 7
    • 5
    • 5
    • 5
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    pSer1033
    适用
    • 183
    • 99
    • 57
    • 18
    • 14
    • 8
    宿主
    • 190
    • 8
    克隆类型
    • 170
    • 28
    多克隆
    标记
    • 81
    • 12
    • 12
    • 9
    • 8
    • 8
    • 8
    • 8
    • 8
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    • 6
    • 5
    • 5
    • 5
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    • 1
    This ASK1 antibody is conjugated to Cy7
    应用范围
    • 157
    • 58
    • 38
    • 38
    • 38
    • 30
    • 29
    • 20
    • 11
    • 11
    • 7
    • 4
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    预测反应
    Human,Mouse,Rat,Dog,Cow,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human ASK1 around the phosphorylation site of Ser1033
    亚型
    IgG
    Top Product
    Discover our top product MAP3K5 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))
    别名
    ASK1 (MAP3K5 产品)
    别名
    ASK1 antibody, MAPKKK5 antibody, MEKK5 antibody, mitogen-activated protein kinase kinase kinase 5 antibody, MUD21.11 antibody, MUD21_11 antibody, 7420452D20Rik antibody, ASK antibody, Mekk5 antibody, Ask1 antibody, RGD1306565 antibody, mitogen-activated protein kinase kinase kinase 5 antibody, MAP3K5 antibody, MAPKKK5 antibody, Map3k5 antibody, map3k5 antibody
    背景

    Synonyms: ASK1 phospho S1033, Mitogen-activated protein kinase kinase kinase 5, MAPK/ERK kinase kinase 5, MEK kinase 5, MEKK 5, Apoptosis signal-regulating kinase 1, ASK-1, MAP3K5, ASK1, MAPKKK5, MEKK5, M3K5_HUMAN.

    Background: Mitogen-activated protein kinase (MAPK) signaling cascades include MAPK or extracellular signal-regulated kinase (ERK), MAPK kinase (MKK or MEK), and MAPK kinase kinase (MAPKKK or MEKK). MAPKK kinase/MEKK phosphorylates and activates its downstream protein kinase, MAPK kinase/MEK, which in turn activates MAPK. The kinases of these signaling cascades are highly conserved, and homologs exist in yeast, Drosophila, and mammalian cells. MAPKKK5 contains 1,374 amino acids with all 11 kinase subdomains. Northern blot analysis shows that MAPKKK5 transcript is abundantly expressed in human heart and pancreas. The MAPKKK5 protein phosphorylates and activates MKK4 (aliases SERK1, MAPKK4) in vitro, and activates c-Jun N-terminal kinase (JNK)/stress-activated protein kinase (SAPK) during transient expression in COS and 293 cells, MAPKKK5 does not activate MAPK/ERK.

    基因ID
    4217
    途径
    MAPK Pathway, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response
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